Date published: 2025-9-6

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Chondroitin Sulfate Supplement for Horses – UltraCruz®

by Santa Cruz Animal Health
4.9(63)
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Promotes Healthy Joints and Connective Tissue
    • Helps maintain normal, healthy cartilage and joint function
    • Ideal for working-, performance- and senior horses
    • Provides Chondroitin as an easy to use pellet
    • Developed and manufactured in the USA with globally-sourced ingredients by Santa Cruz Animal Health
    • Highly recommended by others, see testimonials in tab below
    • Same day shipping on orders received before 3:30 PM Central Time Monday-Friday.
    • DISCOUNT: Bulk orders of UltraCruz® Animal Health products totaling $500 or more receive a 5% discount.
Catalog #DescriptionPriceQtyAutoshipCARTFAVORITES
sc-516452
4 lb, pellet, 32 day supply
$29.95Autoship: $28.45
sc-516453
10 lb, pellet, 80 day supply
$75.95Autoship: $72.15
sc-520054
1 lb, powder, 129 day supply
$35.95Autoship: $34.15
sc-520059
4 lb MSM, 4 lb Glucosamine Sulfate, 1 lb Chondroitin Sulfate bundle, powder
$89.14Autoship: $84.68
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UltraCruz® Equine Chondroitin Sulfate Supplement for Horses

  • May help reduce inflammation associated with training and competition
  • Supports connective tissue and joints

UltraCruz® Equine Chondroitin Sulfate Supplement for Horses is a pelleted formula designed to support healthy joints and cartilage in horses. Although cartilage is a very resilient tissue and can tolerate considerable stress and heavy loads, it has no blood vessels or nerves and therefore has a limited healing ability when injured.

Chondroitin Sulfate Supplement for Horses - Teddy Robinson Riding Shiners Diamond Girl

References:

  1. Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate.  |  Orth, MW., et al. 2002. Equine Vet J Suppl. 224-9. PMID: 12405691
  2. The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse.  |  Du, J., et al. 2004. Biopharm Drug Dispos. 25: 109-16. PMID: 15083499
  3. Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism.  |  Dechant, JE., et al. 2005. Equine Vet J. 37: 227-31. PMID: 15892231
  4. Urinary glycosaminoglycans in horse osteoarthritis. Effects of chondroitin sulfate and glucosamine.  |  Baccarin, RY., et al. 2012. Res Vet Sci. 93: 88-96. PMID: 21925689
  5. Effects of hyaluronan alone or in combination with chondroitin sulfate and N-acetyl-d-glucosamine on lipopolysaccharide challenge-exposed equine fibroblast-like synovial cells.  |  Kilborne, AH., et al. 2017. Am J Vet Res. 78: 579-588. PMID: 28441052
  6. Avocado/Soybean Unsaponifiables, Glucosamine and Chondroitin Sulfate Combination Inhibits Proinflammatory COX-2 Expression and Prostaglandin E2 Production in Tendon-Derived Cells.  |  Grzanna, MW., et al. 2020. J Med Food. 23: 139-146. PMID: 31486703
  7. The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture  |  J.I Fenton, K.A Chlebek-Brown, T.L Peters, J.P Caron, M.WOrth. 2000. Osteoarthritis and Cartilage. Volume 8, Issue 6: 444-451.
  8. Glucosamine and Chondroitin Sulfate  |  Karla L. Miller, Daniel O.Clegg. 2011. Rheumatic Disease Clinics of North America. Vol 37, Issue 1: 103-118.
  9. The Effect of Glucosamine and Chondroitin on Stressed Equine Cartilage Explants  |  R.S.Harlan, R.C.Haut, M.W.Orth. 2012. Journal of Equine Veterinary Science. Volume 32, Issue 1: 12-14.

Pellet vs. Powder Supplement Formulations

UltraCruz® Supplements are now available in pelletized formulations. By using pellets, rather than powder, we have been able to:

Chondroitin Sulfate Supplement for Horses - Piles of Equine Supplement pellets
  • Ensure stability of active ingredients
  • Maximize product freshness
  • Reduce waste

All San Juan Ranch performance and breeding horses use UltraCruz® Equine pelletized products.

loader

can the pellets be given as one dose rather than twice daily?

Asked by: Pellet dosing
Hi, It is recommended that you administer one scoop twice per day.
Answered by: SCAH Representative
Date published: 2022-07-06

Can you tell me the source of the Chondroitin, bovine, shark, porcine?

Asked by: Callon
Hello, The Chondroitin is sourced from Shark. Thank you, SCAHealth
Answered by: SCAH Representative
Date published: 2022-06-08

Can I give this to my dog? 33lb.mini Australian Shepherd. My vet wants me to get him the injections, but I would rather not. 

Asked by: Wilda
Hello, THis product is labeled for equine use only, we do not recommend this product for dogs. Thank you, SCAHealth
Answered by: SCAH Representative
Date published: 2022-02-02

How much chondroitin does a scoop of the pellets provide?  How much does a scoop of the powder provide?

Asked by: lwg808
Hello! Both the pellets and the powder contain 3,500 mg of Chondroitin Sulfate per recommended daily dosage (2 scoops)
Answered by: SCAH Rep
Date published: 2020-07-24
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Rated 5 out of 5 by from Perfect joint supplement!I compared pretty much all the big name joint supplements on the market and was disappointed to realize NONE of them contain ideal amounts and ratios of glucosamine, chondroitin, and MSM. I was ecstatic when I happened upon the UltraCruz joint products because not only do they dose at the level recommended to keep my horses’ joints healthy, the price is literally unbeatable. My horses eat this right up in their grain without question. The chondroitin (and all the joint products) come with a handy little scoop and I feel so much better knowing my horses are getting what they need to function their best, and at a price that is so good I am still shocked.
Date published: 2021-03-14
Rated 5 out of 5 by from Very Helpful!We have been giving our 23-year-old horse MSM and glucosamine supplements for some time, but he didn't seem to be moving as freely as we thought he should. Giving him the UltraCruz Equine Chondroitin Sulfate Supplement made the difference we were looking for. I would highly recommend this product!
Date published: 2018-11-09
Rated 5 out of 5 by from Small doses a Day!I’ve been using UltraCruz’s Chondroitin Sulfate for years, in conjunction with Glucosamine and MSM. I like making my own mixture so finding it pure is a blessing. Having to only use a small scoop a day, it lasts a long time. And we have been joint free now for years - thanks to this regimen.
Date published: 2019-02-25
Rated 5 out of 5 by from Great for our hard workersThis is giving daily to my endurance horses. The scoop is super small so you aren't using a lot at all and they eat it just fine. I use this in conjunction with MSM and Glucosamine which I do buy separately do to needed to withdraw the MSM before race weekends per our rules.
Date published: 2017-02-20
Rated 4 out of 5 by from You get what you pay forChondroitin sulfate is an important component of many equine joint supplements. However, these supplements do not always contain the recommended dosage. With pure chondroitin sulfate, I can add the correct amount to my senior equines feed.
Date published: 2017-06-10
Rated 5 out of 5 by from Cost effective!Loving having the ingredients pure and alone for my horse. You cannot beat the price and the customer service of Santa Cruz!
Date published: 2017-02-14
Rated 5 out of 5 by from Wonderful ProductThe shipping was fast, the products were fresh and my horse loves to eat his food with these products in it which is hard to find! his joint stiffness is no longer noticeable and he’s feeling great! I will buy my joint products from this company only!
Date published: 2020-06-04
Rated 5 out of 5 by from Great for Cushings horseI have a 25-year-old horse with Cushing’s and this is a nice way to provide some joint support without risking adverse effects related to his Cushings. Palatable as well!
Date published: 2022-12-12
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Chondroitin Sulfate Supplement for Horses – UltraCruz is rated 4.9 out of 5 by 52.
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