Date published: 2026-6-10

1-800-457-3801

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Chondroitin Sulfate Supplement for Horses – UltraCruz®

by Santa Cruz Animal Health
4.9(66)
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Promotes Healthy Joints and Connective Tissue
    • Helps maintain normal, healthy cartilage and joint function
    • Ideal for working-, performance- and senior horses
    • Provides Chondroitin as an easy to use pellet
    • Developed and manufactured in the USA with globally-sourced ingredients by Santa Cruz Animal Health
    • Highly recommended by others, see testimonials in tab below
    • Same day shipping on in-stock items ordered before 3:00 PM Central Time Monday-Friday.
    • DISCOUNT: Bulk orders of UltraCruz® Animal Health products totaling $500 or more receive a 5% discount.
Catalog #DescriptionPriceQtyAutoshipCARTFAVORITES
sc-516452
4 lb, pellet, 32 day supply
$29.95Autoship: $28.45
sc-516453
10 lb, pellet, 80 day supply
$75.95Autoship: $72.15
sc-520054
1 lb, powder, 129 day supply
$49.95Autoship: $47.45
sc-520059
4 lb MSM, 4 lb Glucosamine Sulfate, 1 lb Chondroitin Sulfate bundle, powder
$104.95Autoship: $99.70
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UltraCruz® Equine Chondroitin Sulfate Supplement for Horses

  • May help reduce inflammation associated with training and competition
  • Supports connective tissue and joints

UltraCruz® Equine Chondroitin Sulfate Supplement for Horses is a pelleted formula designed to support healthy joints and cartilage in horses. Although cartilage is a very resilient tissue and can tolerate considerable stress and heavy loads, it has no blood vessels or nerves and therefore has a limited healing ability when injured.

Chondroitin Sulfate Supplement for Horses - Teddy Robinson Riding Shiners Diamond Girl

References:

  1. Inhibition of articular cartilage degradation by glucosamine-HCl and chondroitin sulphate.  |  Orth, MW., et al. 2002. Equine Vet J Suppl. 224-9. PMID: 12405691
  2. The bioavailability and pharmacokinetics of glucosamine hydrochloride and chondroitin sulfate after oral and intravenous single dose administration in the horse.  |  Du, J., et al. 2004. Biopharm Drug Dispos. 25: 109-16. PMID: 15083499
  3. Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism.  |  Dechant, JE., et al. 2005. Equine Vet J. 37: 227-31. PMID: 15892231
  4. Urinary glycosaminoglycans in horse osteoarthritis. Effects of chondroitin sulfate and glucosamine.  |  Baccarin, RY., et al. 2012. Res Vet Sci. 93: 88-96. PMID: 21925689
  5. Effects of hyaluronan alone or in combination with chondroitin sulfate and N-acetyl-d-glucosamine on lipopolysaccharide challenge-exposed equine fibroblast-like synovial cells.  |  Kilborne, AH., et al. 2017. Am J Vet Res. 78: 579-588. PMID: 28441052
  6. Avocado/Soybean Unsaponifiables, Glucosamine and Chondroitin Sulfate Combination Inhibits Proinflammatory COX-2 Expression and Prostaglandin E2 Production in Tendon-Derived Cells.  |  Grzanna, MW., et al. 2020. J Med Food. 23: 139-146. PMID: 31486703
  7. The effects of glucosamine derivatives on equine articular cartilage degradation in explant culture  |  J.I Fenton, K.A Chlebek-Brown, T.L Peters, J.P Caron, M.WOrth. 2000. Osteoarthritis and Cartilage. Volume 8, Issue 6: 444-451.
  8. Glucosamine and Chondroitin Sulfate  |  Karla L. Miller, Daniel O.Clegg. 2011. Rheumatic Disease Clinics of North America. Vol 37, Issue 1: 103-118.
  9. The Effect of Glucosamine and Chondroitin on Stressed Equine Cartilage Explants  |  R.S.Harlan, R.C.Haut, M.W.Orth. 2012. Journal of Equine Veterinary Science. Volume 32, Issue 1: 12-14.

Pellet vs. Powder Supplement Formulations

UltraCruz® Supplements are now available in pelletized formulations. By using pellets, rather than powder, we have been able to:

Chondroitin Sulfate Supplement for Horses - Piles of Equine Supplement pellets
  • Ensure stability of active ingredients
  • Maximize product freshness
  • Reduce waste

All San Juan Ranch performance and breeding horses use UltraCruz® Equine pelletized products.

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